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Where it comes from: sea shells or synthetic
Glucosamine is a naturally-occurring molecule found in the human body. It is present in the synovial fluid which is responsible for joint lubrification. In some arthritic diseases, there is a lack of synovial fluid which causes pain, swelling and reduced joint mobility.
Several salts of glucosamine are commercially available, such as sulfate, hydrochloride and others. Since most studies have been performed on glucosamine sulfate, the efficacy of these other salts has not been established.
Oral glucosamine is absorbed at a rate of about 90%.
Symptoms relief appear within 4 to 6 weeks and its long-term safety and efficacy have not been established.
Used doses: 500 mg, orally, 3 times a day.
There is insufficient reliable information to conclude that glucosamine is effective in any other indication.
In 2004, Canada adopted new regulations that control the manufacturing, packaging, labeling and importing of natural health products. The new regulations also include an adverse reaction reporting system. Products that conform to the regulation's criteria are identified with a natural product number (NPN) and can be legally sold in Canada. This number indicates that the product meets specific criteria for safety and purity, not that it is effective for any indication.
Medicinal plant contents vary naturally from plant to plant - just as fruits from the same package may vary in taste and texture. There is no standard to measure the active content of each plant. Thus, efficacy of natural products should be expected to vary from brand to brand as well as from bottle to bottle of the same brand.
For more information about the Natural Health Products Regulations, or to check if a product has been assessed, visit the Health Canada website at www.hc-sc.gc.ca/dhp-mps/prodnatur/index-eng.php.
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The patient information leaflets are provided by Vigilance Santé Inc. This content is for information purposes only and does not in any manner whatsoever replace the opinion or advice of your health care professional. Always consult a health care professional before making a decision about your medication or treatment.